OP Labs Ipamorelin 5mg pentapeptide research compound lyophilized powder in glass vial
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Ipamorelin 5mg

£15.52

Ipamorelin is a specialised research peptide used in scientific investigation of growth hormone secretagogue activity, selective ghrelin receptor (GHS-R1a) signalling, and neuroendocrine regulatory pathways.

OP Labs formerly Oxford Peptides
Batch tested Purity: ≥ 99 % (HPLC, typical)
CAS Number: 170851-70-4
Molecular Formula: C₃₈H₄₉N₉O₅

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  • Amino Acid Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2 (C-terminal amide; Aib = a-aminoisobutyric acid)
(461 customer reviews)

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OP Labs Ipamorelin 5mg pentapeptide research compound lyophilized powder in glass vial
Ipamorelin 5mg
£15.52

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden.

Ipamorelin
Certificate of Analysis (representative)

Representative specimen data. These are typical results for this product. Actual results are batch-specific and are printed on the certificate for the batch number on your vial. Research use only.

Ipamorelin — representative Certificate of Analysis (specimen)
ParameterResult
Product nameIpamorelin
CAS number170851-70-4
Molecular formulaC38H49N9O5
Molecular weight711.85 g/mol
AppearanceWhite to off-white powder
Test methodRP-HPLC (C18), UV detection at 220 nm
Purity (HPLC)98.85% (specification ≥ 98.5%)
Mass-spec identityESI-MS (positive): [M+H]+ 712.9, confirming 711.85 g/mol
Water content3.3% (Karl Fischer, specification ≤ 10.0%)
Analysis dateRepresentative specimen — the analysis date is printed on each batch certificate

Download the specimen certificate (PDF)

  • OP Labs formerly Oxford Peptides
  • Batch HPLC tested at 98.5%+ purity
  • Store frozen long term or in fridge when ready to be used
  • Sold for research purposes only
  • Contact us for Wholesale Orders

Search our database for full COA analytics here.

Ipamorelin

Synonyms / Designations: Ipamorelin, Ipamorelin Acetate, NNC 26-0161, Ipamorelin pentapeptide
CAS Number: 170851-70-4
Molecular Formula: C38H49N9O5
Molecular Weight: ~711.85 g/mol
Peptide Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Peptide Classification: Synthetic growth hormone secretagogue; selective ghrelin receptor agonist
Purity: ≥ 99 % (HPLC, typical)
Appearance: White to off-white lyophilised powder
Pack Size: 5 mg
Storage: Desiccated, protected from light, stored at –20 °C
Solubility: Soluble in sterile water and buffered aqueous solutions

Description & Mechanism

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue derived from GHRP-1 through structural optimisation. It was the first selective growth hormone-releasing peptide (GHRP) receptor agonist developed, demonstrating selectivity similar to that of growth hormone-releasing hormone (GHRH) for stimulating growth hormone release.

In biochemical and cellular research systems, ipamorelin acts as an agonist at the ghrelin/growth hormone secretagogue receptor (GHSR-1a) expressed on pituitary somatotroph cells. Unlike earlier GHRP compounds such as GHRP-6 and GHRP-2, ipamorelin exhibits a distinct selectivity profile: experimental studies have demonstrated that it does not release adrenocorticotropic hormone (ACTH) or cortisol at growth hormone-stimulating concentrations. This selectivity makes ipamorelin a valuable research tool for investigating GH secretion pathways independently of hypothalamic-pituitary-adrenal (HPA) axis activation. In animal models, ipamorelin has been reported to induce longitudinal bone growth in a dose-dependent manner under controlled experimental conditions.

Applications in Research

  • Investigation of GHSR-1a receptor binding, selectivity, and signalling pathways
  • Study of growth hormone secretagogue mechanisms independent of HPA axis activation
  • Research into pituitary somatotroph function and GH release dynamics
  • In vitro and in vivo comparison with other GHRP compounds (GHRP-2, GHRP-6, Hexarelin)
  • Models examining GH/IGF-1 axis regulation and bone growth signalling
  • Use as a selective reference compound in neuroendocrine and peptide signalling research

Handling, Reconstitution & Stability

  • Weigh under dry conditions; peptide is hygroscopic
  • Reconstitute in sterile water or appropriate buffered aqueous solution depending on assay requirements
  • Avoid vigorous agitation during dissolution
  • Filter sterilize if required (e.g. 0.22 µm) immediately prior to use
  • Aliquot and store reconstituted solutions at –20 °C (or lower) to minimise degradation
  • Avoid repeated freeze–thaw cycles

Specifications Summary

Purity (HPLC): ≥ 99 %
Appearance: White to off-white lyophilised powder
Peptide Type: Synthetic growth hormone secretagogue (GHSR-1a agonist)
Molecular Formula: C38H49N9O5
Molecular Weight: ~711.85 g/mol
Solubility: Water, buffered aqueous solutions
Storage: –20 °C, desiccated, protected from light
Pack Size: 5 mg

Precautions & Notes

  • Experimental behaviour of ipamorelin is influenced by receptor expression, concentration, and exposure duration
  • Unlike GHRP-6 and GHRP-2, ipamorelin does not stimulate ACTH or cortisol release at GH-stimulating concentrations
  • Buffer composition, pH, and ionic strength may affect peptide stability and assay performance
  • Appropriate controls are recommended to distinguish receptor-specific from non-specific effects
  • Intended strictly for laboratory research use; not for human or veterinary application

References

Raun K. et al. Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 1998.
https://pubmed.ncbi.nlm.nih.gov/9849822/

Sinha D.K. et al. Beyond the androgen receptor: the contribution of growth hormone secretagogues to changes in body composition. Growth Hormone & IGF Research, 2020.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7108996/

Johansen P.B. et al. Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Hormone & IGF Research, 1999.
https://pubmed.ncbi.nlm.nih.gov/10373343/

Keywords: Ipamorelin, Ipamorelin Acetate, NNC 26-0161, Growth Hormone Secretagogue, GHSR-1a Agonist, Ghrelin Receptor Agonist, Selective GHRP, Synthetic Peptide, Neuroendocrine Research

461 reviews for Ipamorelin 5mg

  1. Robert Patterson (Verified Purchase) –

    Great value as always

  2. Dez (Verified Purchase) –

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  4. Dean Jarmos (Verified Purchase) –

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  11. Jonny Teasdale (Verified Purchase) –

  12. Simon (Verified Purchase) –

  13. Janis (Verified Purchase) –

    Great service as always!

  14. Simon (Verified Purchase) –

  15. Sam (Verified Purchase) –

    Not used as yet

  16. Miroslaw –

  17. Matt (Verified Purchase) –

    Bought a few times works as it should Just wish they sold blends with cjc as well

  18. David (Verified Purchase) –

    Always a good company, quick delivery and never any issues

  19. SH (Verified Purchase) –

    One of my favourites. OP company delivers what it promises.

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  21. Jon (Verified Purchase) –

    Excellent product

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    Does exactly what you want it to do . I have been researching over a year and had nothing but good results with OP.

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  29. Aaron (Verified Purchase) –

    Amazing quality! And amazing results (on my lab rat) I said it before but I’ll say it again OP definitely has one of the highest, purist, quality range!

  30. Anonymous (Verified Purchase) –

  31. Sebastian (Verified Purchase) –

    Best in UK!

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  34. Anonymous (Verified Purchase) –

    It’s good for sleep and gh

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  36. Anonymous –

    Good quality and effective.

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  38. Anonymous –

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    Excellent product

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    Excellent product

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  42. Tom –

    Perfect

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    Ordering was EASY.. delivery was immediate.. THANK YOU.. I’ll be using your amazing products & services regular

  44. Troy Wear –

    I havent tried it yet but your service, speed of delivery and packaging where all excellent

  45. Nigel Royston –

    Good compound, would like to see 99% purity though

  46. Bryn Anderson –

  47. Reece Byfield –

  48. Andrew C. –

  49. chen yu tsang –

    very good product and service

  50. Anonymous –

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    Great communication.

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    Always fast delivery and seen great results

  54. Gavin –

    Amazing results

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  56. Rory C. –

    High quality product as always

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    Great product and very timely delivery.

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  59. Anonymous –

    Excellent. Used at 500mcg/day in combination with CJC1295 200mcg/day

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  63. Niall Donaghy –

    Early days on this one, using it to support BPC-157 and TB-500 for tendon recovery. Not sure of the effects but can say that this stack is already working after a few days. Curious to see if sleep improves or gym progress improves.

  64. Jamie B. –

    2nd cycle going extremely well!

  65. Anonymous –

  66. barrie swaine –

    One of the tb 500 and a bottle of lpamorelin was cloudy in its dry form and looked like some separation had occurred I’m currently on day 3 of no reply and the chat bot isn’t fit for purpose

  67. Pearl –

    Well packaged. Good high-quality product. Arrived very quickly.

  68. Anonymous –

  69. Anne Mclachlan –

    Good product

  70. james shanks –

  71. GARRY BLACKSTONE –

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    Delivery was fast and the product is great.

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    Delivery was faster than I expected.

  79. Lily –

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    So pleased with this purchase.

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    Does the job perfectly.

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    Wasn’t impressed with the slow delivery.

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    Not worth the wait, considering the shipping time.

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    Really low-quality product.

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    Really low-quality product.

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    DoesnÕt work as advertised.

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    It felt like forever waiting for this.

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    The quality just isnÕt there.

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    Very disappointed in the slow delivery.

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    Delivery was delayed, very frustrating.

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    Amazing, ordering again!

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    Bought this a few times

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    Amazing, ordering again!

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    Great item, arrived very quickly.

  287. Anonymous –

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    They sent me different peptides than I had ordered. But luckily, I wanted to buy those other peptides in the future anyway. I’ve been using OP peptides for a long time, they work, and I’m satisfied.

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    Works best at night fasted 2 hours before bed.

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    Love the product it’s self small shipping delay but I can’t complain

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    Package arrived late, unacceptable.

  355. Sydney King –

    Product came fast, love the quality.

  356. Joanne N. –

    Quick delivery, great value for money.

  357. Caroline Shaw –

    Came fast, couldnÕt ask for more.

  358. Naiomi –

    Quick delivery, perfect condition.

  359. Anna C. –

    Shipping took way too long.

  360. Anonymous –

    Fast delivery, couldnÕt be happier.

  361. Claire Hunt –

    Not pleased with the shipping time.

  362. Stephanie –

    Quick shipping, great service.

  363. Jackie O. –

    Not worth waiting this long for the product.

  364. Charlotte –

    CouldnÕt be more satisfied.

  365. Barbie S. –

    Great product, would buy again.

  366. Emma –

    Worth every penny..

  367. Barb Clifford –

    Just love it.

  368. Fiona H. –

    Excellent value for money.

  369. Rhonagh –

    Completely satisfied.

  370. Richard H. –

    Totally recommend it.

  371. Anonymous –

    Great quality product.

  372. Jacqueline –

    Does exactly what it says.

  373. Felicity –

    ItÕs a lifesaver.

  374. Jennifer Hughes –

    Five stars.

  375. Debbie Edwards –

    Arrived fast, amazing product.

  376. Michael H. –

    Quick delivery and love the product.

  377. Anonymous –

    Very fast delivery, love the product.

  378. Naemi Kumar –

    Excellent product and fast delivery.

  379. Sarah Clarke –

    Fast delivery, super pleased.

  380. Holly Ward –

    Arrived so fast, very happy!

  381. Susan C. –

    Delivery was incredibly fast!

  382. Alexander P. –

    IÕm really pleased with this.

  383. Anonymous –

    Really disappointed with the quality.

  384. Nicola B. –

    Love the features.

  385. Matthew Gray –

    Love this item.

  386. Emma Hartwell –

    A must-buy.

  387. Nicola M. –

    WouldnÕt recommend because of the delivery time.

  388. Kristine –

    Just incredible.

  389. Fanni F. –

    Delivery was much slower than expected.

  390. Creon Menzies –

    Best in the market.

  391. Sara Lamont –

    I highly recommend this.

  392. Tom –

    Fast delivery, very satisfied with my purchase.

  393. Anonymous –

    Arrived quickly, exactly what I wanted.

  394. Anonymous –

    Fast delivery, works great for me.

  395. Nathalie Smith –

    Arrived quickly, love the quality.

  396. Jo-Ann –

    Super fast shipping, very happy.

  397. Richard Mawer –

    Fast delivery, exceeded expectations.

  398. Lorna –

    Fast delivery, super pleased.

  399. Anonymous –

    Ridiculously slow delivery.

  400. Scott Cooksley –

    Fast shipping, just as described.

  401. Anonymous –

  402. Robyn –

    Love using this.

  403. Amanda –

    ItÕs perfect.

  404. Gillian –

    Absolutely love the quality.

  405. Marine –

    Not worth the wait.

  406. isabel –

    Performs better than I thought.

  407. Louise Williams –

    IÕm loving this product.

  408. Phoenix –

    Brilliant value.

  409. Monique –

    Works perfectly every time.

  410. Eamon B. –

    Excellent choice.

  411. Ben –

    Unbelievably slow delivery.

  412. Anonymous –

    Very efficient.

  413. Anonymous –

    Very impressed with this.

  414. adam clarke –

    Excellent value for money.

  415. Antonia A. –

  416. Jade F. –

    Way too slow, wonÕt order again.

  417. Sam Morris –

    IÕm obsessed.

  418. chris watts –

    So glad I bought this.

  419. Toni –

    No regrets.

  420. Laura K. –

    Great addition to my collection.

  421. Anonymous –

    Very versatile.

  422. Rachel –

    Shipping took way too long.

  423. virginia evans –

    Absolutely perfect.

  424. Sarah Stanbrook –

    Delivers as promised.

  425. Jarrad Harries –

    Not pleased with the shipping time.

  426. Callum Rothero –

    No complaints at all.

  427. Chloe Womack –

    Does exactly what it says.

  428. Francisco Lima –

    Totally satisfied.

  429. SARAH LEADSOM –

    Just awesome.

  430. Holly –

    Exactly what I needed.

  431. Jack S. –

    Absolutely love the quality.

  432. Rebecca A. –

    Very happy with the performance.

  433. Emily Walsh –

    Delivery was delayed, very frustrating.

  434. Anonymous –

    IÕm blown away by the quality.

  435. Tammy –

    IÕm thrilled with the results.

  436. Luke N. –

    Very practical product.

  437. Alex Thomas –

    It took forever to get here.

  438. Kirsten Stewart –

    Totally dependable.

  439. Mr P Vache –

    Very happy, arrived very fast. Thank you.

  440. Rhianna D. –

    Highly satisfied.

  441. Ian Bridle –

    The quality just isnÕt there.

  442. Ashley G. –

    Exactly what I needed.

  443. James –

    Totally satisfied with this.

  444. Megan Guinan –

    IÕm amazed by how well this works.

  445. Katie Hodges –

    Feels like I wasted my money.

  446. Emily –

  447. Michelle Dunstan –

    IÕm so impressed.

  448. Elizabeth H. –

    Absolutely love using it.

  449. Harriet Brannelly –

    CanÕt go wrong with this.

  450. Mark –

    Got it so fast, very satisfied.

  451. Anonymous –

    Came faster than expected, very happy.

  452. Chris H. –

    Seriously, what took so long?

  453. Nic –

    Extremely satisfied.

  454. Aiden –

    DidnÕt last as long as it should.

  455. Neil Marshall –

    Performs wonderfully.

  456. Sarah B. –

    So glad I bought it.

  457. Samantha M. –

    Could have arrived faster.

  458. Gill Prentis –

    Exceeded expectations.

  459. Clyde –

    Excellent craftsmanship.

  460. Catherine T. –

    Totally worth it.

  461. Craig W. –

    Highly recommend.

Only logged in customers who have purchased this product may leave a review.

SKU: 604565856074 Category: Brand:

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