- OP Labs formerly Oxford Peptides
- Batch HPLC tested at ≥ 99% purity
- Storage: –20 °C long term; 2–8 °C short term
- Sold for research purposes only
Vilon
Synonyms / Designations: Vilon; KE; Lys-Glu; L-lysyl-L-glutamic acid; synthetic short peptide
CAS Number: 45234-02-4
Molecular Formula: C11H21N3O5
Molecular Weight: 275.30 g/mol
Purity: ≥ 99% (HPLC)
Appearance: White to off-white lyophilised powder
Pack Size: 20 mg (total)
Storage: Desiccated, protected from light, stored at –20 °C or below
Solubility: Soluble in water and buffered aqueous solutions
Description & Mechanism
Vilon (Lys-Glu) is studied in vitro as a minimal immune/thymic-directed peptide probe. It has been reported to affect structural and facultative heterochromatin in cultured human lymphocytes, increasing the proportion of transcriptionally active euchromatin and reactivating nucleolar organiser regions in cultured cells — used experimentally to study epigenetic and chromatin-level regulation of gene expression.
It has been studied as a co-activator of specific genes in gene-regulation studies. Frequently cited as one of the shortest peptides reported to show biological activity, it is used as a reference “minimal peptide” in structure–activity studies. Observed effects are dependent on concentration, model system and exposure conditions.
Applications in Research
- In-vitro chromatin-structure / heterochromatin studies in human lymphocytes
- Epigenetic gene-reactivation and gene-expression research
- Reference “minimal peptide” probe for structure–activity studies
Specifications Summary
| Parameter | Typical Value / Range |
|---|---|
| Purity (HPLC) | ≥ 99% |
| Appearance | White to off-white lyophilised powder |
| Molecular Weight | 275.30 g/mol |
| Peptide Type | Synthetic dipeptide |
| Solubility | Water, buffered aqueous solutions |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 20 mg (total) |
Precautions & Notes
- Experimental behaviour is dependent on concentration, model system and exposure conditions
- Appropriate experimental controls are recommended
- Prolonged exposure to light, elevated temperature or aqueous environments may reduce stability
- Intended strictly for laboratory research use; not for human or veterinary application
References
Khavinson VKh, Popovich IG, et al. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22):7053.
https://www.mdpi.com/1420-3049/26/22/7053
PubChem Compound Summary, CID 7010502 (Lysylglutamic acid, Lys-Glu).
https://pubchem.ncbi.nlm.nih.gov/compound/7010502
Keywords: Vilon, KE, Lys-Glu, short peptide
