OP Labs TB-500 Thymosin Beta-4 5mg research peptide lyophilized powder in glass vial
TB-500 5mg - Image 2
TB-500 5mg - Image 3
quality consistency 99% purity shipped from freezer 24 month shelf life
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TB-500 5mg

£18.40

TB-500 is generally referenced in research catalogs as fequesetide (an active-region peptide of thymosin β4), used experimentally to investigate actin dynamics, cell migration, and repair-associated signalling pathways in controlled laboratory systems.

  • OP Labs formerly Oxford Peptides
  • Batch tested Purity: ≥ 99 % (HPLC, typical)
  • CAS Number: 77591-33-4
  • Molecular Formula: C212H350N56O78S
  • Amino Acid Sequence: Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES (thymosin beta-4, 43-mer, N-acetylated)
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(385 customer reviews)

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OP Labs TB-500 Thymosin Beta-4 5mg research peptide lyophilized powder in glass vial
TB-500 5mg
£18.40

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden.

TB-500
Certificate of Analysis (representative)

Representative specimen data. These are typical results for this product. Actual results are batch-specific and are printed on the certificate for the batch number on your vial. Research use only.

TB-500 — representative Certificate of Analysis (specimen)
ParameterResult
Product nameTB-500
CAS number77591-33-4
Molecular formulaC212H350N56O78S
Molecular weight4963.0 g/mol
AppearanceWhite to off-white powder
Test methodRP-HPLC (C18), UV detection at 220 nm
Purity (HPLC)98.96% (specification ≥ 98.5%)
Mass-spec identityESI-MS (positive): [M+4H]4+ 1241.9, confirming 4963.0 g/mol
Water content7.1% (Karl Fischer, specification ≤ 10.0%)
Analysis dateRepresentative specimen — the analysis date is printed on each batch certificate

Download the specimen certificate (PDF)

  • OP Labs formerly Oxford Peptides
  • Batch HPLC tested at 98.5%+ purity
  • Store frozen long term or in fridge when ready to be used
  • Sold for research purposes only
  • Contact us for Wholesale Orders

Search our database for full COA analytics here.

TB-500

Synonyms / Designations: TB-500, Thymosin Beta-4 Fragment, Synthetic Thymosin b4–Derived Peptide
CAS Number: 77591-33-4
Molecular Formula: C212H350N56O78S
Molecular Weight: ~4963.0 g/mol
Peptide Length: 43 amino acids
Peptide Type: Synthetic peptide derived from thymosin beta-4
Purity: 99 % (HPLC, typical)
Appearance: White to off-white lyophilised powder
Pack Size: 5 mg (typical)
Storage: Desiccated, protected from light, stored at –20 °C or below
Solubility: Soluble in water and buffered aqueous solutions

Description & Mechanism

TB-500 is a synthetic peptide derived from the active region of thymosin beta-4, developed for experimental investigation of actin-binding dynamics, cell migration, and cytoskeletal organisation in controlled research settings.

In biochemical and cellular research models, thymosin beta-4–related peptides are studied for their interaction with G-actin, influencing actin polymerisation and cytoskeletal remodelling. Observed responses depend on peptide concentration, exposure duration, cell type, and experimental conditions.

Applications in Research

• Investigation of actin dynamics and cytoskeletal regulation
• In vitro studies of cell migration and cellular organisation
• Experimental models examining tissue structure and repair signalling
• Reference peptide in thymosin beta-4–related research

Handling, Reconstitution & Stability

  • Weigh under dry conditions; peptide may be hygroscopic.
  • Reconstitute in sterile water or appropriate buffered aqueous solution.
  • Avoid vigorous agitation during dissolution.
  • Filter sterilize if required.
  • Aliquot and store reconstituted solutions at –20 °C or lower.
  • Avoid repeated freeze–thaw cycles.

Precautions & Notes

  • Experimental outcomes depend on cell type and assay conditions.
  • Buffer composition, pH, and ionic strength may influence peptide stability.
  • Appropriate controls are recommended.
  • Intended strictly for laboratory research use only.

References

Gupta S., Paliczak A., Delgado D. Evidence-based indications of thymosin beta-4 for wound healing and tissue regeneration. Annals of the New York Academy of Sciences, 2021.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8228050/

Sosne G., Qiu P., Goldstein A.L., Wheater M. Biological activities of thymosin beta-4 defined by active sites in short peptide sequences. FASEB Journal, 2010.
https://iovs.arvojournals.org/article.aspx?articleid=2423767

Malinda K.M., Sidhu G.S., Mani H. et al. Thymosin beta-4 accelerates wound healing. Journal of Investigative Dermatology, 1999.
https://pubmed.ncbi.nlm.nih.gov/10469335/

Keywords: TB-500, Thymosin Beta-4, Synthetic Peptide, Actin Regulation, Cytoskeletal Dynamics, Research Peptide

385 reviews for TB-500 5mg

  1. MALIK (Verified Purchase) –

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    Not responding to my complaint. They dont bother to rectify issues once you have paid for order

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    Very fast delivery and very good peptides, they do what they are supposed to. Also no allergy reaction/red spots on skin

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  230. Anonymous –

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    Works really well, very happy

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    Still waiting for delivery

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  374. Sasha –

    IÕve had faster deliveries from other places.

  375. Gabrielle Darne‚Äô –

    Excellent choice.

  376. Kirsten Stewart –

    Best quality ever.

  377. Ann Elwood –

    ItÕs a lifesaver.

  378. Sarah C. –

    Totally love it.

  379. Andrea G. –

    Highly recommend.

  380. Mx P M Kitcher –

    IÕm loving this product.

  381. Jane Runnett –

    Absolutely fantastic.

  382. Timothy –

    Just incredible.

  383. Vince Chiappinelli –

    Took way too long to arrive.

  384. Federica R. –

    Super happy with my purchase.

  385. Karen –

    Exceeded my expectations.

Only logged in customers who have purchased this product may leave a review.

SKU: 604565855657 Category: Brand:

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