OP Labs AOD9604 2mg research peptide lyophilized powder in glass vial
OP Labs research peptides
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AOD9604 2mg

£19.90

AOD9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone, used as a research tool in experimental systems.

  • OP Labs formerly Oxford Peptides
  • Batch tested Purity: ≥ 98 % (HPLC, typical)
  • CAS Number: 221231-10-3
  • Molecular Formula: C78H123N23O23S2
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(56 customer reviews)

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OP Labs AOD9604 2mg research peptide lyophilized powder in glass vial
AOD9604 2mg
£19.90

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden.

  • OP Labs formerly Oxford Peptides.
  • Batch HPLC tested at 99%+ purity.
  • Store frozen long term or in fridge when ready to be used.
  • Sold for research purposes only.
  • Contact us for Wholesale Orders.

Download COA here: AOD9604_2mg.pdf
Please note: if you have a different Batch ID, please contact us for the latest COA.

AOD9604

Synonyms / Designations: AOD9604, Synthetic hGH Fragment (176–191), Modified C-terminal Growth Hormone Peptide.
CAS Number: 221231-10-3.
Molecular Formula: C78H123N23O23S2.
Molecular Weight: ~1,815.1 g/mol.
Purity: ≥ 99 % (HPLC).
Appearance: White to off-white lyophilised powder.
Pack Size: 2 mg (total).
Storage: Desiccated, protected from light, stored at –20 °C or below.
Solubility: Soluble in water and buffered aqueous solutions.

Description & Mechanism

AOD9604 is a synthetic peptide derived from the C-terminal fragment (residues 176–191) of human growth hormone (hGH), with sequence modifications introduced to enhance stability and research utility. Unlike full-length growth hormone, AOD9604 does not directly activate the growth hormone receptor but is studied as a discrete molecular fragment with distinct biological activity in experimental systems.

In biochemical and cellular research models, AOD9604 is used to investigate growth hormone–related signalling pathways that are independent of classical GH receptor activation. Preclinical studies have shown that this peptide fragment can influence pathways associated with lipid metabolism and intracellular signalling without eliciting broad growth hormone–mediated effects. Observed outcomes are dependent on experimental context, concentration, and model design, making AOD9604 a useful tool for mechanistic studies examining domain-specific activity of growth hormone–derived peptides.

Applications in Research

  • As a molecular tool to study growth hormone fragment–specific signalling mechanisms.
  • Investigation of lipid metabolism–associated pathways in cellular and biochemical models.
  • In vitro studies examining receptor-independent growth hormone signalling.
  • Preclinical or ex vivo research exploring structure–function relationships of GH-derived peptides.

Specifications Summary

ParameterTypical Value / Range
Purity (HPLC)≥ 98%
AppearanceWhite to off-white lyophilised powder
Molecular Weight~1,815.1 g/mol
Peptide TypeSynthetic hGH fragment
SolubilityWater, buffered aqueous solutions
Storage–20 °C, desiccated, dark
Pack Size2 mg

 

Handling, Reconstitution & Stability

  • Weigh under dry conditions; peptide is hygroscopic.
  • Reconstitute in sterile water or appropriate buffered aqueous solution depending on assay requirements.
  • Avoid vigorous agitation during dissolution.
  • Filter sterilize if required (e.g. 0.22 µm) prior to use.
  • Aliquot and store reconstituted solutions at –20 °C or below to minimise degradation.
  • Avoid repeated freeze–thaw cycles.

Precautions & Notes

  • AOD9604 activity is concentration- and context-dependent; appropriate dose–response controls are recommended.
  • As a peptide fragment, behaviour may differ from full-length growth hormone in receptor or signalling assays.
  • Prolonged exposure to light, elevated temperature, or aqueous environments may reduce stability.
  • Intended strictly for laboratory research use; not for human or veterinary application.

References

Chance W.T. et al. Pancreatic polypeptide and its fragments: receptor interactions and biological activity. Peptides, 1995.
https://pubmed.ncbi.nlm.nih.gov/8594255/

Michel M.C. et al. Neuropeptide Y and pancreatic polypeptide receptors. Pharmacological Reviews, 1998.
https://pubmed.ncbi.nlm.nih.gov/9597167/

Balasubramaniam A. Pancreatic polypeptide and related peptides. Endocrine Reviews, 2003.
https://pubmed.ncbi.nlm.nih.gov/12700199/

Keywords: AOD9604, hGH Fragment 176–191, Growth Hormone Peptide, Modified C-terminal Growth Hormone Peptide.

56 reviews for AOD9604 2mg

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