- OP Labs formerly Oxford Peptides.
- Batch HPLC tested at 99%+ purity.
- Store frozen long term or in fridge when ready to be used.
- Sold for research purposes only.
- Contact us for Wholesale Orders.
Download COA here: CJC-1295 without DAC COA.pdf
Please note if you have a different Batch ID please contact us for the latest COA.
CJC-1295 (Without DAC)
Synonyms: CJC-1295, Modified GHRH (1–29) analogue, Tetrasubstituted GHRH (1–29), Growth Hormone–Releasing Hormone analogue.
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.9 g/mol (approximate)
CAS Number: 446262-90-4
Peptide Classification: Synthetic growth hormone–releasing hormone (GHRH 1–29) analogue.
Solubility: Soluble in sterile water, acetic acid, and physiological buffers (e.g., PBS)
Description & Mechanism
CJC-1295 without DAC is a synthetic analogue of growth hormone–releasing hormone (GHRH 1–29) incorporating amino acid substitutions designed to enhance stability relative to the native peptide. Unlike DAC-conjugated variants, CJC-1295 does not contain a drug affinity complex and therefore exhibits pharmacokinetic behaviour characteristic of non-conjugated GHRH analogues in experimental systems.
In biochemical and cellular research models, CJC-1295 interacts with the GHRH receptor expressed on pituitary-derived cells, initiating intracellular signalling cascades associated with endocrine regulation. Preclinical and clinical research has examined receptor binding properties, activation kinetics, and downstream signalling under short-duration exposure conditions. Observed molecular and physiological responses are dependent on experimental design, concentration, and model system, and are used to investigate GHRH receptor signalling rather than defined biological or physiological outcomes.
Applications in Research
- As a molecular probe to study GHRH receptor binding and activation dynamics.
- Investigation of growth hormone axis signalling and endocrine feedback mechanisms.
- In cellular assays examining downstream transcriptional and signalling responses.
- In preclinical or clinical research models assessing extended peptide–receptor interaction resulting from albumin association.
Handling, Reconstitution & Stability
- Weigh under dry conditions; peptide is hygroscopic.
- Reconstitute in sterile water or appropriate buffered aqueous solution depending on assay requirements.
- Avoid vigorous agitation during dissolution due to peptide–DAC conjugation.
Filter sterilize if required (e.g. 0.22 µm) immediately prior to use. - Aliquot and store reconstituted solutions at –20 °C (or lower) to avoid repeated freeze–thaw cycles.
- Inspect solutions for precipitation or changes in clarity before use in sensitive assays
Specifications Summary
| Parameter | Typical Value / Range |
|---|---|
| Purity (HPLC) | ≥ 98% |
| Appearance | White to off-white lyophilised powder |
| Molecular Weight | ~3,647.9 g/mol |
| Peptide Type | Synthetic GHRH analogue with DAC |
| Solubility | Water, buffered aqueous solutions |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 2 mg |
References
- Teichman, S. L., Neale, A., Lawrence, D., et al. (2006). “Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone.” Journal of Clinical Endocrinology & Metabolism, 91(3), 799–805. https://doi.org/10.1210/jc.2005-1536
- Wu, Z., et al. (2009). “Synthesis and characterization of growth hormone releasing hormone analogues.” Peptides, 30(5), 783–789. https://doi.org/10.1016/j.peptides.2009.01.010
- Frohman, L. A., Downs, T. R., Heimer, E. P., et al. (1989). “Studies of the biological activity of analogs of growth hormone-releasing factor (GRF).” Endocrinology, 124(1), 279–284. https://doi.org/10.1210/endo-124-1-279
- Camanni, F., Ghigo, E., Arvat, E. (1998). “Growth hormone-releasing peptides and their analogs.” Frontiers in Neuroendocrinology, 19(1), 47–72. https://doi.org/10.1006/frne.1997.0166
Keywords: CJC-1295 without DAC, CJC without DAC, CJC no DAC, CJC1295 no DAC, CJC1295 without DAC.










David Moir –
Works for me before bed good combined with bpc.
Anonymous –
Robert Gaunt (verified owner) –
Very happy with this product seems to be working well
Anonymous (verified owner) –
Charlie –
Amazing product, very good results 🙂
Alex –
David C. –
Egidijus Eidukas –
Danny Toolan –
Scott Manuel –
I love it
Joseph T. –
Anonymous –
Connor T. –
Anonymous –
Great quality product. Very fast shipping!!
Kate R. –
Sleep so much better! Great product. Delivered quickly, well packaged, highly recommend OP Labs.
Karen P. –
Anonymous –
Steve Walters –
Excellent
Em D. –
chen yu tsang –
very good product and service
Chris S. –
Brilliant product and service
Darius J. –
Fast delivery.
Jonathan Lee –
Anonymous –
Very good results with 200mcg/day. Used in combination with Ipamorelin 500mcg/day.
Jamie M. –
Brilliant service. Fast delivery and product is legit
Anonymous –
Didn’t really notice anything, not sure of the purity
barrie swaine –
Pearl –
Well packaged. Good high-quality product. Arrived very quickly.
Anonymous –
james shanks –
Rhiannon Cooper –
Happy with this purchase.
Scott –
Fantastic product.
L E J. –
Works like a charm.
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Fast delivery, very satisfied with my purchase.
Jennifer –
Got it fast, very pleased with the quality.
Tina Appleton –
Arrived much faster than I expected.
Alexandra –
Came so fast, amazing service.
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Super fast delivery!
Bronty L. –
Delivery was quicker than anticipated.
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Speedy delivery, works perfectly.
Megan –
Delivery was faster than I expected.
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Totally satisfied with this.
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This is really great quality.
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Best value ever.
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Highly reliable.
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CanÕt recommend this enough.
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Very happy with the performance.
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Truly excellent.
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Perfect for what I needed.
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Worth every penny..
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CouldnÕt be better.
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Totally recommend this product.
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This is a must-have.
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Quality is amazing.
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Love using this.
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Love using this.
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CanÕt live without it now.
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Fantastic product quality.
Emma Grice –
Simply amazing.
Mrs J. –
Best quality ever.
Wiktoria Pipczynska –
Works flawlessly.
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Love everything about it.
Byron De Winter –
Highly satisfied.
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Quick delivery, product is amazing.
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Fast delivery, fantastic product.
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Fast delivery, works great for me.
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Arrived fast, amazing product.
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Fast delivery and works perfectly.
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Fast shipping and amazing quality.
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Got it fast, love it.
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The best product IÕve ever used.
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Amazing quality.
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Very dependable.
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Very satisfied.
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ItÕs a winner.
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Love using this.
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Totally love it.
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IÕm completely sold.
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This is awesome.
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This is amazing quality.
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IÕm very pleased.
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Fast delivery and works great.
Andrew –
Incredibly fast shipping, thank you!
Ankit Mahendru –
Super quick delivery, love the product.
Lauren –
Great product, highly recommend.
Rhoslyn –
This is really great quality.
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Very durable and reliable.
Charlene McNabb –
A great product.
Kirsty –
Exactly as described.
Philip Worrall –
CanÕt recommend enough.
Anonymous –
Works incredibly well.
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ItÕs perfect.
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Super convenient.
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Extremely happy with my choice.
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IÕm so happy I bought this.
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Fantastic product.
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Product came fast, love the quality.
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Delivery was quicker than anticipated.
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Came fast, couldnÕt ask for more.
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Delivery was fast and the product is great.
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Fast delivery, great value.
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Fast delivery and excellent product.
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Fast shipping and amazing quality.
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Arrived quicker than expected.
Lauren –
Best quality ever.
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Very high-quality.
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Very dependable.
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IÕm beyond thrilled.
Purdy Basra –
A fantastic investment.
Kate White –
Just incredible.
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CouldnÕt ask for a better product.
Sue L. –
Awesome purchase.
Ian –
Five stars.
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Got it fast, highly satisfied.
Anonymous –
This product rocks.
Olivia S. –
ItÕs a perfect fit.
Delme –
Works perfectly every time.
Keith R Byrne –
The quality is outstanding.
Macarena F. –
No complaints at all.
christina G. –
Very happy with this.
Ashton Leung –
Totally recommend this product.
Georgina –
CouldnÕt ask for more.
Nicole –
This is a must-have.
karen –
Completely satisfied.
Elise –
Love the design.
Joshua Yardley –
Works great.
Anonymous –
Super helpful.
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Wonderful product.
Gemma –
ItÕs a winner.
Anonymous –
Fast delivery, couldnÕt be happier.
Samuel H. –
Best quality ever.
Anonymous –
IÕm beyond thrilled.
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I love how this works.
Morgan –
Outstanding quality.
Beth Jackson –
Fast delivery, just what I needed.
Natalie –
Got it so fast, very satisfied.
Kyle D. –
Very practical product.
Emma Payne –
Feels like a waste of money.
Lauren Battle –
Very slow shipping, not happy at all.
Ellis M. –
Too slow for my liking.
Jude H. –
It felt like forever waiting for this.
Toni –
Not impressed with the shipping speed.
Lisa Hoey –
Took forever to ship.
Elizabeth Owen –
I could have walked here faster.
Mel M. –
Very disappointed in the slow delivery.
Katrina D. –
Very slow shipping, not happy at all.
Tim D. –
Extremely slow shipping.
Lucy –
For this price, it should be better.
Morgan rees –
It stopped working already.
Lisa A. –
IÕve bought better for cheaper.
Jake Bingham –
Definitely not what I was hoping for.
Paula –
Not worth the price tag.
Janet –
Very slow shipping, not happy at all.
Clement –
Wasn’t happy with how long it took.
Anonymous –
Totally disappointed in the quality.
Anonymous –
It didnÕt meet my expectations.
Anonymous –
Not pleased with the shipping time.
Margot C. –
Not impressed with the shipping speed.
Callum W. –
Feels like a waste of money.
Shawn –
fast, good prices, results – enjoy getting my orders every time!
Mark Buck –
Great quality product and fast delivery.
Trevor Hurley –
Very fast delivery, just hope the Pep tides are as good as the service so far.
Calvin Bogie –
Matt Webb –
Awesome service
Matt Webb –
Steven –
Happy to reccomend.
Anonymous –
John Russell –
Anonymous –
Sean M. –
Very good
Glenn –
Don’t buy. I think they’re not real. Dodgy packaging. No contact number or email and the chat bot doesn’t respond.
Phil Booth –
I like this product and it worksgreat along Ipamorelin, but i i would rather have a 4 or 5 mg vial to match the Ipa 5mg one. I manage by getting 2 x 2mg per bottle of Ipa. Thats my only reason for giving it a 4/5 and not a 5/5. Very fast delivery and their response to my email about putting the wrong address details on was quick and very professional. I keep coming back every month.
Sophie K. –
Well worth it.
Anastacia –
Works wonderfully.
susan craker –
Very effective.
Fiona –
Love using this.
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Shipping should not take this long in 2024.
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Just love how it works.
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Extremely happy with my choice.
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ItÕs a perfect fit.
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Amazing quality.
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Best in the market.
Emma M. –
Best decision ever.
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Fast delivery, product is perfect.
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Lightning fast shipping, highly recommend.
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Quick delivery, great quality.
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Just love how it works.
Verified Buyer –
Shipping should not take this long in 2024.
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Love the features.
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Excellent craftsmanship.
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Very practical product.
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Extremely happy with this.
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Why does delivery take so long these days?
Emma –
Super happy with my purchase.
Thomas B. –
Very useful and practical.
Verified Buyer –
Frustrated with how slow the shipping was.
Fiona H. –
Happy with this purchase.
Emma –
This is amazing.
Saffron W. –
Happy with this purchase.
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Very pleased with this.
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ItÕs perfect.
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Super fast shipping, very happy.
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Fast delivery and works perfectly.
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Absolutely fantastic.
Alexander P. –
Very high-end.
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Totally recommend this product.
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This is awesome.
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I use it all the time.
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Very durable and reliable.
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Very high-quality.
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ItÕs just fantastic.
Alice Thorne –
Really low-quality product.
kai –
Speedy shipping, exactly what I needed.
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Got it so fast, very satisfied.
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Quick delivery, perfect condition.
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Delivery was quicker than anticipated.
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Highly recommend.
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Delivery took way too long to be acceptable.
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This product is the best.
Anonymous –
Totally dependable.
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The quality is outstanding.
Helen G. –
Love the results.
michelle schmidt –
CanÕt go wrong with this.
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Works incredibly well.
Anonymous –
Lives up to the hype.
Autumn Mogford-Abbott –
I could have walked here faster.
Toni –
I use it all the time.
Anonymous –
Super helpful.
Rachel –
Works flawlessly.
Sarah Stanbrook –
IÕm very impressed.
Lara –
Super useful.
Emily Grace –
So glad I bought it.
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Very pleased with this.
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Great performance.
Alex Tait –
Does the job perfectly.
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Awesome quality.
Ailsa –
Amazing value for money.
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Excellent quality product.
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Great purchase.
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CanÕt recommend this enough.
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Super happy with this.
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Fantastic product.
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A must-have.
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It works so well.
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Very underwhelming product.
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I wonÕt be buying this again.
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Super happy I found this.
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I use it all the time.
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I expected a lot more from this product.
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IÕm beyond thrilled.
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Highly reliable.
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Does the trick.
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IÕm so happy I bought this.
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Great design and quality.
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Absolutely love this.
Clyde –
Simply amazing.