OP Labs TB-500 Thymosin Beta-4 5mg research peptide lyophilized powder in glass vial
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TB-500 5mg

£23.90

TB-500 is generally referenced in research catalogs as fequesetide (an active-region peptide of thymosin β4), used experimentally to investigate actin dynamics, cell migration, and repair-associated signalling pathways in controlled laboratory systems.

  • OP Labs formerly Oxford Peptides
  • Batch tested Purity: ≥ 99 % (HPLC, typical)
  • CAS Number: 77591-33-4
  • Molecular Formula: C212H350N56O78S
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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden.

  • OP Labs formerly Oxford Peptides
  • Batch HPLC tested at 99%+ purity
  • Store frozen long term or in fridge when ready to be used
  • Sold for research purposes only
  • Contact us for Wholesale Orders

Download COA here: TB-500_COA.pdf
Please note: if you have a different Batch ID, please contact us for the latest COA.

TB-500

Synonyms / Designations: TB-500, Thymosin Beta-4 Fragment, Synthetic Thymosin b4–Derived Peptide
CAS Number: 77591-33-4
Molecular Formula: C212H350N56O78S
Molecular Weight: ~4963.0 g/mol
Peptide Length: 43 amino acids
Peptide Type: Synthetic peptide derived from thymosin beta-4
Purity: 99 % (HPLC, typical)
Appearance: White to off-white lyophilised powder
Pack Size: 5 mg (typical)
Storage: Desiccated, protected from light, stored at –20 °C or below
Solubility: Soluble in water and buffered aqueous solutions

Description & Mechanism

TB-500 is a synthetic peptide derived from the active region of thymosin beta-4, developed for experimental investigation of actin-binding dynamics, cell migration, and cytoskeletal organisation in controlled research settings.

In biochemical and cellular research models, thymosin beta-4–related peptides are studied for their interaction with G-actin, influencing actin polymerisation and cytoskeletal remodelling. Observed responses depend on peptide concentration, exposure duration, cell type, and experimental conditions.

Applications in Research

• Investigation of actin dynamics and cytoskeletal regulation
• In vitro studies of cell migration and cellular organisation
• Experimental models examining tissue structure and repair signalling
• Reference peptide in thymosin beta-4–related research

Handling, Reconstitution & Stability

  • Weigh under dry conditions; peptide may be hygroscopic.
  • Reconstitute in sterile water or appropriate buffered aqueous solution.
  • Avoid vigorous agitation during dissolution.
  • Filter sterilize if required.
  • Aliquot and store reconstituted solutions at –20 °C or lower.
  • Avoid repeated freeze–thaw cycles.

Precautions & Notes

  • Experimental outcomes depend on cell type and assay conditions.
  • Buffer composition, pH, and ionic strength may influence peptide stability.
  • Appropriate controls are recommended.
  • Intended strictly for laboratory research use only.

References

Gupta S., Paliczak A., Delgado D. Evidence-based indications of thymosin beta-4 for wound healing and tissue regeneration. Annals of the New York Academy of Sciences, 2021.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8228050/

Sosne G., Qiu P., Goldstein A.L., Wheater M. Biological activities of thymosin beta-4 defined by active sites in short peptide sequences. FASEB Journal, 2010.
https://iovs.arvojournals.org/article.aspx?articleid=2423767

Malinda K.M., Sidhu G.S., Mani H. et al. Thymosin beta-4 accelerates wound healing. Journal of Investigative Dermatology, 1999.
https://pubmed.ncbi.nlm.nih.gov/10469335/

Keywords: TB-500, Thymosin Beta-4, Synthetic Peptide, Actin Regulation, Cytoskeletal Dynamics, Research Peptide

SKU: 0604565855657 Category: Brand:

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