OP Labs PE-22-28 5mg research peptide lyophilized powder in glass vial
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PE-22-28 5mg

£23.90

PE-22-28 is a specialised research peptide developed for experimental investigation of pancreatic polypeptide–related signalling, peptide–receptor interactions, and neuroendocrine regulatory pathways.

  • OP Labs formerly Oxford Peptides
  • Batch tested Purity: ≥ 98.5 % (HPLC, typical)
  • CAS Number: 1801959-12-5
  • Molecular Formula: C35H55N11O9
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(88 customer reviews)

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OP Labs PE-22-28 5mg research peptide lyophilized powder in glass vial
PE-22-28 5mg
£23.90

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies are performed outside of the body. These products are not medicines or drugs and have not been approved to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden.

PE-22-28
Certificate of Analysis (representative)

Representative specimen data. These are typical results for this product. Actual results are batch-specific and are printed on the certificate for the batch number on your vial. Research use only.

PE-22-28 — representative Certificate of Analysis (specimen)
ParameterResult
Product namePE-22-28
CAS number1801959-12-5
Molecular formulaC35H55N11O9
Molecular weight773.89 g/mol
AppearanceWhite to off-white powder
Test methodRP-HPLC (C18), UV detection at 220 nm
Purity (HPLC)98.64% (specification ≥ 98.5%)
Mass-spec identityESI-MS (positive): [M+H]+ 774.9, confirming 773.89 g/mol
Water content6.7% (Karl Fischer, specification ≤ 10.0%)
Analysis dateRepresentative specimen — the analysis date is printed on each batch certificate

Download the specimen certificate (PDF)

  • OP Labs formerly Oxford Peptides.
  • Batch HPLC tested at 98.5%+ purity.
  • Store frozen long term or in fridge when ready to be used.
  • Sold for research purposes only.
  • Contact us for Wholesale Orders.

Search our database for full COA analytics here.

PE-22-28

Synonyms / Designations: PE-22-28, Pancreatic Polypeptide (22–28) fragment, PP(22–28), C-terminal pancreatic polypeptide fragment
CAS Number: 1801959-12-5
Molecular Formula: C35H56N12O9
Molecular Weight: ~773.89 g/mol
Peptide Sequence: Arg–Pro–Tyr–Leu–Gly–Pro–Arg
Peptide Classification: Synthetic peptide fragment derived from pancreatic polypeptide (PP)
Purity: ≥ 99 % (HPLC, typical)
Appearance: White to off-white lyophilised powder
Pack Size: 5 mg (typical)
Storage: Desiccated, protected from light, stored at –20 °C
Solubility: Soluble in water and buffered aqueous solutions

Description & Mechanism

PE-22-28 is a synthetic peptide corresponding to amino acids 22–28 of pancreatic polypeptide (PP), an endogenous peptide hormone involved in neuroendocrine signalling. The fragment represents a structurally defined region commonly used in research to study sequence-specific peptide–receptor interactions independent of the full-length parent molecule.

In biochemical and cellular research systems, PE-22-28 has been investigated for its interaction with Y-family peptide receptors and its role in modulating peptide signalling pathways associated with pancreatic and neuroendocrine communication. Experimental observations are dependent on model system, receptor expression, concentration, and exposure duration, and are used to explore signalling mechanisms rather than defined physiological outcomes.

Applications in Research

  • As a molecular probe for studying pancreatic polypeptide–derived signalling
  • Investigation of Y-receptor binding and peptide–receptor interaction dynamics
  • In vitro studies examining structure–function relationships of PP fragments
  • Use as a reference compound in neuroendocrine and peptide signalling research

Specifications Summary

Purity: ≥ 99 %
Appearance: White to off-white lyophilised powder
Peptide Type: Synthetic pancreatic polypeptide fragment
Molecular Weight: ~773.89 g/mol
Solubility: Water, buffered aqueous solutions
Storage: –20 °C, desiccated, protected from light
Pack Size: 5 mg

Precautions & Notes

  • Experimental behaviour of PE-22-28 is influenced by receptor expression and assay conditions
  • Peptide fragments may exhibit signalling profiles distinct from full-length pancreatic polypeptide
  • Buffer composition, pH, and ionic strength may affect peptide stability
  • Appropriate experimental controls are recommended
  • Intended strictly for laboratory research use; not for human or veterinary application

References

Chance W.T. et al. Pancreatic polypeptide and its fragments: receptor interactions and biological activity. Peptides, 1995.
https://pubmed.ncbi.nlm.nih.gov/8594255/

Michel M.C. et al. Neuropeptide Y and pancreatic polypeptide receptors. Pharmacological Reviews, 1998.
https://pubmed.ncbi.nlm.nih.gov/9597167/

Balasubramaniam A. Pancreatic polypeptide and related peptides. Endocrine Reviews, 2003.
https://pubmed.ncbi.nlm.nih.gov/12700199/

Keywords: PE-22-28, Pancreatic Polypeptide Fragment, PP(22–28), Y-Receptor Peptide, Synthetic Peptide

88 reviews for PE-22-28 5mg

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SKU: 604565856043 Category: Brand:

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