- OP Labs formerly Oxford Peptides
- Batch HPLC tested at 99%+ purity
- Store frozen long term or in fridge when ready to be used
- Sold for research purposes only
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Download COA here: Prostamax_20mg.pdf
Please note: if you have a different Batch ID, please contact us for the latest COA.
Prostamax
Synonyms / Designations: Prostamax; KEDP; Lys-Glu-Asp-Pro; prostate peptide bioregulator
Amino Acid Sequence: Lys-Glu-Asp-Pro (KEDP)
CAS Number: N/A
Molecular Formula: C20H33N5O9
Molecular Weight: 487.51 g/mol
Purity: ≥ 99 % (HPLC)
Appearance: White to off-white lyophilised powder
Pack Size: 20 mg (total)
Storage: Desiccated, protected from light, stored at –20 °C or below
Solubility: Soluble in water and buffered aqueous solutions
Description & Mechanism
Prostamax (KEDP) is studied in vitro as a prostate-tissue-directed short-peptide probe, used to examine how a minimal defined peptide signal influences transcriptional, proteomic and proliferation/apoptosis endpoints in prostate-derived cell populations.
Within the Khavinson model, peptides of this class are proposed to act at the chromatin level to modulate tissue-specific gene-expression patterns in experimental aging models. It is used as a comparator/tool compound for tissue-specificity studies; observed effects depend on concentration, model system and exposure conditions.
Applications in Research
- In-vitro investigation of prostate-derived cell proliferation / apoptosis markers
- Tissue-specificity comparison across organ-directed bioregulators
- Preclinical rodent models of age-related prostatic change
- Probe for short-peptide transcriptional regulation in genitourinary tissue
Specifications Summary
| Parameter | Typical Value / Range |
|---|---|
| Purity (HPLC) | ≥ 99 % |
| Appearance | White to off-white lyophilised powder |
| Molecular Weight | 487.51 g/mol |
| Peptide Type | Synthetic tetrapeptide bioregulator (Khavinson-class; prostate) |
| Solubility | Water, buffered aqueous solutions |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 20 mg (total) |
Handling, Reconstitution & Stability
- Weigh under dry conditions; peptide is hygroscopic
- Reconstitute in sterile water or appropriate buffered aqueous solution depending on assay requirements
- Avoid vigorous agitation during dissolution
- Filter sterilize if required (e.g. 0.22 µm) prior to use
- Aliquot and store reconstituted solutions at –20 °C or below to minimise degradation
- Avoid repeated freeze–thaw cycles
Precautions & Notes
- Experimental behaviour is dependent on concentration, model system and exposure conditions
- Appropriate experimental controls are recommended
- Prolonged exposure to light, elevated temperature or aqueous environments may reduce stability
- Intended strictly for laboratory research use; not for human or veterinary application
References
Khavinson VKh, Popovich IG, et al. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22):7053.
https://www.mdpi.com/1420-3049/26/22/7053
Khavinson VKh. Peptides and ageing. Neuro Endocrinol Lett. 2002;23(Suppl 3):11-144.
https://pubmed.ncbi.nlm.nih.gov/12374906/
Patent RU2177802C1 — Tetrapeptide regulating prostate function.
https://patents.google.com/patent/RU2177802C1/en
Keywords: Prostamax, KEDP, prostate peptide bioregulator, synthetic tetrapeptide
