- OP Labs formerly Oxford Peptides
- Batch HPLC tested at ≥ 99% purity
- Storage: –20 °C long term; 2–8 °C short term
- Sold for research purposes only
Ovagen
Synonyms / Designations: Ovagen; EDL; Glu-Asp-Leu
Amino Acid Sequence: Glu-Asp-Leu (EDL)
CAS Number: N/A
Molecular Formula: C15H25N3O8
Molecular Weight: 375.38 g/mol
Purity: ≥ 99% (HPLC)
Appearance: White to off-white lyophilised powder
Pack Size: 20 mg (total)
Storage: Desiccated, protected from light, stored at –20 °C or below
Solubility: Soluble in water and buffered aqueous solutions
Description & Mechanism
Ovagen (EDL) is studied in vitro as a short tissue-specific peptide probe for hepatic and gastrointestinal epithelial signalling. In experimental models it is proposed to enter cells and act at the chromatin/transcriptional level, modulating expression of genes associated with hepatocyte proliferation and epithelial homeostasis.
EDL serves as a reference compound for testing tissue-selective effects on proliferation/apoptosis markers (e.g. Ki-67, p53) in cultured tissue. It is a molecular probe; observed effects depend on concentration, model system and exposure conditions.
Applications in Research
- In-vitro study of hepatocyte / GI-epithelial gene-expression regulation in organotypic cultures
- Comparative tissue-specificity screening across related short peptides
- Reference probe for short-peptide chromatin / transcription studies
Specifications Summary
| Parameter | Typical Value / Range |
|---|---|
| Purity (HPLC) | ≥ 99% |
| Appearance | White to off-white lyophilised powder |
| Molecular Weight | 375.38 g/mol |
| Peptide Type | Synthetic linear tripeptide |
| Solubility | Water, buffered aqueous solutions |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 20 mg (total) |
Precautions & Notes
- Experimental behaviour is dependent on concentration, model system and exposure conditions
- Appropriate experimental controls are recommended
- Prolonged exposure to light, elevated temperature or aqueous environments may reduce stability
- Intended strictly for laboratory research use; not for human or veterinary application
References
Khavinson VKh, Popovich IG, et al. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22):7053.
https://www.mdpi.com/1420-3049/26/22/7053
PubChem Compound Summary, CID 444128 (Glu-Asp-Leu).
https://pubchem.ncbi.nlm.nih.gov/compound/444128
Keywords: Ovagen, EDL, synthetic tripeptide
