- OP Labs formerly Oxford Peptides
- Batch HPLC tested at ≥ 99% purity
- Storage: –20 °C long term; 2–8 °C short term
- Sold for research purposes only
Crystagen
Synonyms / Designations: Crystagen; Kristagen; EDP; synthetic short peptide
Amino Acid Sequence: Glu-Asp-Pro (EDP)
CAS Number: N/A
Molecular Formula: C14H21N3O8
Molecular Weight: 359.34 g/mol
Purity: ≥ 99% (HPLC)
Appearance: White to off-white lyophilised powder
Pack Size: 20 mg (total)
Storage: Desiccated, protected from light, stored at –20 °C or below
Solubility: Soluble in water and buffered aqueous solutions
Description & Mechanism
Crystagen is a short synthetic tripeptide (EDP), used as a molecular probe for studying immune / lymphoid gene regulation in experimental systems. In cellular models it is studied for effects on lymphocyte proliferation and T-cell-associated markers (e.g. CD3+, CD4+ populations and the CD4+/CD8+ ratio).
EDP is studied as a cell-penetrating peptide that may bind double-stranded DNA and/or histones to influence expression of immune-system genes. It functions in the laboratory as a research probe for short-peptide / chromatin interaction and immune gene-expression studies; observed effects depend on concentration, model system and exposure conditions.
Applications in Research
- In-vitro lymphocyte proliferation and T-cell marker assays (CD3+/CD4+, CD4+/CD8+)
- Cellular models of immune / thymic gene regulation and immunosenescence
- Studies of EDP as a defined active component of the Thymalin peptide complex
- Probe for short-peptide DNA/histone-binding studies
Specifications Summary
| Parameter | Typical Value / Range |
|---|---|
| Purity (HPLC) | ≥ 99% |
| Appearance | White to off-white lyophilised powder |
| Molecular Weight | 359.34 g/mol |
| Peptide Type | Synthetic linear tripeptide |
| Solubility | Water, buffered aqueous solutions |
| Storage | –20 °C, desiccated, dark |
| Pack Size | 20 mg (total) |
Precautions & Notes
- Experimental behaviour is dependent on concentration, model system and exposure conditions
- As an immunomodulatory research peptide, appropriate experimental controls are recommended
- Prolonged exposure to light, elevated temperature or aqueous environments may reduce stability
- Intended strictly for laboratory research use; not for human or veterinary application
References
Khavinson VKh, Linkova NS, et al. Short cell-penetrating peptides: a model of interactions with gene promoter sites.
https://pubmed.ncbi.nlm.nih.gov/23484211/
Khavinson VKh, Popovich IG, et al. Peptide Regulation of Gene Expression: A Systematic Review. Molecules. 2021;26(22):7053.
https://www.mdpi.com/1420-3049/26/22/7053
Keywords: Crystagen, EDP, short peptide, synthetic tripeptide
